Edward is the Joan and Sanford Weill Chair of Neurological Surgery at UCSF, specializing in epilepsy, brain tumors, and advanced brain mapping. He co-directs the Center for Neural Engineering and Prostheses, a UCSF–UC Berkeley collaboration developing biomedical technology to restore function for patients with paralysis and speech disorders.
His research focuses on the neural mechanisms of speech, movement, and emotion. He earned the Blavatnik National Laureate for Life Sciences in 2015 and was inducted into the National Academy of Medicine (2020) and National Academy of Sciences (2025).